Nucleofill Polynucleotide Injections
Nucleofill Medium and Strong are CE-certified polynucleotide injectables that stimulate collagen, boost hydration, and treat scars, stretch marks and early signs of ageing — administered in-clinic by licensed practitioners.
Nucleofill Polynucleotide Injections

Nucleofill is a CE-certified injectable polynucleotide treatment, administered exclusively by licensed practitioners. Unlike serums or creams, it works beneath the skin's surface — stimulating collagen and elastin production, improving hydration, and supporting tissue repair from within.
Nucleofill Medium vs Nucleofill Strong
Nucleofill Medium (2% polynucleotide concentration) targets light to moderate wrinkles, such as perioral lines and cheek creases, plus medium-sized scars and stretch marks.
Nucleofill Strong (2.5% polynucleotide concentration) is formulated for moderate to advanced signs of ageing, working more intensively beneath the skin to stimulate collagen and elastin production.
What It Treats
- Skin dehydration
- Scars
- Stretch marks
- Fine lines and wrinkles
- Early to advanced signs of ageing
Frequently Asked Questions
What is Nucleofill?
Nucleofill is a CE-certified injectable polynucleotide treatment administered exclusively by licensed practitioners. It works beneath the skin's surface to stimulate collagen and elastin production, improve hydration, and support tissue repair.
What's the difference between Nucleofill Medium and Nucleofill Strong?
Nucleofill Medium (2% polynucleotide concentration) targets light to moderate wrinkles, such as perioral lines and cheek creases, plus medium-sized scars and stretch marks. Nucleofill Strong (2.5% concentration) is formulated for moderate to advanced signs of ageing, working more intensively beneath the skin.
Is Nucleofill the same as your Polynucleotides Treatment?
Nucleofill is a specific, CE-certified injectable product line used as part of our polynucleotide treatments. Our general Polynucleotides Treatment page covers the broader treatment category; this page focuses specifically on the Nucleofill Medium and Strong injectables.